Morphological monitoring of human small bowel allografts.
نویسندگان
چکیده
منابع مشابه
Histologic monitoring of human small bowel allografts with clinical correlation.
ADV ANCES in surgical techniques and the introduction of the newer. more powerful immunosuppressants have resulted in the successful clinical application of small bowel transplantation. 1-3 This study focused 011 the routine histologic monitoring of small bowel allografts using serial endoscopic biopsies. Histopathologic findings, effectiveness. and the limitations of mucosal biopsies as a moni...
متن کاملSuccessful orthotopic small bowel transplantation with short-term FK 506 immunosuppressive therapy.
A LTHOUGH small bowel transplantation is the physiologic treatment of the short bowel syndrome, Its clinical implementation awaits development of immunosuppressive regimens that ensure satisfactory control of graft rejection. Agents such as Cy A and corticosteroids are useful for transplantation of most other vascularized organ allografts. However, rejection of the transplanted small intestine ...
متن کاملPosttransplant lymphoproliferative disorders in small bowel allograft recipients.
WE HAVE PREVIOUSLY estimated a 20% frcquency of Epstein-Barr virus (EBV) related posttransplant lymphoproliferative disorders (PTLD) in small bowel allograft recipients. I The present study compares rates of PTLD among pediatric and adult recipients of isolated or composite small bowel allografts. We also report PTLD frequency before and after the institution of quantitative EBV monitoring and ...
متن کاملSerum levels of interleukin-6, tumor necrosis factor-alpha, and interleukin-2 in rejecting human small bowel allografts.
CYTOKINES play critical roles in the immune response, particularly in the self-defense system. Activated human monocyte/macrophage is a major source of interleukin-6 (lL-6) and tumor necrosis factor-alpha (TNFa). I Interleukin-2 HL-2) is released primarily by activated T lymphocytes following antigen presentation.2 We conducted a study to monitor various cytokines (IL-6. TNF-a, and IL-2) after ...
متن کاملLymphocyte trafficking using in situ hybridization and physioanatomy of the intestinal immune system after human small bowel transplantation.
THE gut-associated lymphoid tissue (GALT) plays a major role in gastrointestinal immunity. but is thought to represent an immunologic obstacle to successful small bowel transplantation. 1 We have shown that the GALT and mesenteric lymph nodes are preferential sites of allograft rejection in animals. most likely because of the high content of passenger leukocytes.: However. with intense immune s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Transplantation proceedings
دوره 25 1 Pt 2 شماره
صفحات -
تاریخ انتشار 1993